Vice President, Global Commercial Strategy Lead, Inflammation & Immunology + Rare Disease

Job description

Position Overview The Vice President, Global Commercial Strategy Lead for Inflammation & Immunology (I&I) and Rare Disease is responsible for driving long-range commercial strategy, portfolio management, and commercial success across both pipeline and inline brands. This role serves as the single, authoritative commercial voice to R&D, Business Development, and US & International Commercial Regions, establishing clear commercial leadership to improve portfolio decision-making and trade-offs, ensure optimal launch and brand marketing strategies, and maximize global patient impact and enterprise value realization for our I&I and Rare Disease portfolio. Reporting to the Global Commercial Strategy Lead, this leader shapes decisions on I&I and Rare Disease portfolio prioritization, lifecycle value optimization, and global marketing strategy. The position partners closely with R&D, Medical Affairs, Global Access & Value, and Regional Commercial teams to deliver breakthrough therapies addressing autoimmune, inflammatory, and rare diseases. Success in this role requires a senior commercial strategist who combines scientific depth with decisive enterprise leadership. This leader must confidently engage in complex scientific and clinical discussions, synthesize insights across R&D, Access, and Commercial teams, and convert them into clear portfolio priorities and differentiated global strategies. With full accountability for value creation, the role requires strong P&L acumen and the ability to make disciplined trade‑offs that optimize lifecycle value, launch success, and long‑term portfolio performance. The I&I and Rare Disease portfolio represents significant strategic value to realizing Pfizer's vision to achieve leadership via breakthroughs in prioritized diseases and biological axes to generate highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally with 22 ongoing clinical studies underway to significantly expand our product portfolio over the next several years. Role Responsibilities 1. Long-Range Strategic Planning & Portfolio Management Develop and execute comprehensive long-range commercial and marketing strategies for I&I and Rare Disease portfolios, encompassing pipeline assets from early development to in-line assets through commercial maturity. Serve as single, authoritative commercial voice to R&D, Commercial Regions, and Business Development strengthening commercial input from early development through launch via participation in I&I Strategy Governance Team to influence clinical development plans and investment decisions. Lead development of business cases for new product launches and lifecycle management investments. 2. Launch Excellence & Commercialization Strategy Lead integrated global launch and marketing strategies coordinating cross-functional teams across R&D, Commercial Regions, Medical, Regulatory, Market Access, and Supply. Drive new product and indication launch readiness planning including market development activities, brand positioning, competitive assessments, and HCP/patient unmet need analysis. Own commercial asset lifecycle strategy for I&I and Rare Disease including implications of new indications and competitive dynamics 3. Commercial Excellence & Brand Strategy Raise the bar on marketing impact, quality, and brand performance by establishing consistently higher, impact-driven standards for strategic outputs and creative excellence Lead proactive market shaping in moments that matter, anticipating and addressing threats with pre-emptive strategies. Steer Commercial prioritization of evidence generation strategies across lifecycle and Regions to enable sharper cross-functional decisions and portfolio value maximization. 4. Cross-Functional Leadership & Governance Provide global strategic direction for in-line assets while enabling regional adaptation and tactical alignment. Own global brand strategy, launch plans, lifecycle management, and core content packages Partner with Global Access & Value (GAV) teams to develop pricing, contracting, and market access strategies that maximize global value of our portfolio. 5. Organizational Leadership & Talent Development Build and lead high-performing Global Commercial Strategy organization of 50+ highly engaged colleagues. Embed culture of cross-functional collaboration ensuring coordinated internal and external stakeholder engagement. Develop future commercial leaders with the capability to operate across full span of commercial development, launch, and in‑line commercialization. Qualifications & Experience Education Bachelor's degree in Life Sciences, Business, Marketing, or related field required MBA or other advanced degree (PhD, MD, PharmD) strongly preferred Professional Experience Minimum 15+ years of successful, progressive marketing, commercial, and/or development experience in pharmaceutical or biotechnology industry Minimum 8-10 years in commercial leadership roles including Global/US/International marketing, commercial development/strategy Experience in both pipeline (pre-launch) and inline (post-launch) brand management spanning early development through commercialization Therapeutic Area & Functional Expertise Brand management experience developing product strategies, positioning programs, and go-to-market plans Product launch experience including global launch planning and execution Portfolio management and strategic planning expertise across multiple therapeutic areas and development stages Demonstrated ability to influence complex development decisions and engage deeply in scientific dialogue. Leadership & Organizational Capabilities Second-line leadership experience with accountability for developing and managing senior leaders Demonstrated ability to lead cross-functional teams and influencing without direct authority while managing complex stakeholder environments Track record of building and developing high-performing teams Strategic & Busines